Cytology
Microscopy Solutions for Cytology and Cytopathology – Detect Diseases on the Cellular Level
Cytopathology or cytology aims to detect diseases on the cellular level by the study of single cells and cell structures. This pathology discipline was founded in 1928 by the Greek medicine pioneer George Papanicolaou who also invented the “Pap smear”. These smear tests are now commonly used in cytopathology where clinical samples from a wide range of body sites are spread and deposited across a glass microscope slide, resulting in a thin film of cells for subsequent staining and examination by light microscopy.
Microscope Requirements
A very good cellular differentiation and clearly visible nuclear details are absolute prerequisites in cytology for carcinoma and tumor cell diagnosis. Cytologists and pathologists rely on crystal-clear images of their samples with the highest color fidelity in brightfield, phase contrast, DIC, or fluorescence. While cytological stains such as Papanicolaou’s (PAP stain), Giemsa, or Romanowski-type result in specific staining of cellular features, it is the optical quality of the microscope, the fidelity of the attached camera for digital documentation, and the ergonomic design of the instrument that can make all the difference when screening patient samples.
Application Examples
- Lung, acquired in brightfield
- Lung, acquired in brightfield, regions of interest are marked
- HER2 centromere, fluorescence contrast, Brockhoff working group, University of Regensburg
- Lung, acquired in brightfield
Further information can be found in the product brochures.
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LLS ROWIAK LaserLabSolutions GmbH
Dr. Heiko Richter
Garbsener Landstraße 10
30419 Hannover
E-Mail: zeiss@lls-rowiak.de
Phone: +49 511 277 2952